Alzheimer´s update: A new human study, published in the Annals of Neurology, found that Alzheimer´s patients have lower levels of a hormone-like molecule known as Irisin in their cerebrospinal fluid…
Female patients with Alzheimer´s had the lowest levels of this protective molecule…
Four previous mouse studies showed the same results…
And in all these studies, increasing the level of Irisin in Alzheimer´s patients reduced their symptoms!
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Scientists believe this could be a new biomarker for Alzheimer´s and potential new treatment angle…
Turns out that Irisin is released by our muscles during exercise, so starting an exercise programme, or intensifying it, could help Alzheimer´s patients manage their symptoms better…
The researchers concluded that regular physical exercise can slow cognitive decline in people at risk for or with Alzheimer’s disease…
Higher Irisin levels in the brain are associated with improved cognitive function and reduced amyloid beta levels…
Scientists believe that Irisin protects against neuroinflammation by acting directly on the glial cells in the brain.
In this latest study, those with Alzheimer´s had lower levels of Irisin in the cerebrospinal fluid compared with people diagnosed with mild cognitive decline, and those who reported a subjective cognitive decline – which tells us that focusing on this molecule may have a therapeutic effect for this hard-to-treat disease…
We also already know that exercise improves cognitive function in general though, so it´s exciting that it´s been proven for Alzheimer´s specifically…
Also having levels tested, could give doctors better insight into their patients´ brain health, although there are other biomarkers that are further down the line from a development point of view…
But who knows, this may be new avenue for the development of new treatments in the future…
Keep reading…
You don´t have to wait for scientists to develop a new treatment to benefit from the effects of Irisin…
Because we know that our bodies already naturally produce and release Irisin when we exercise, we already have the ability to benefit from this homone-like molecule without having to wait for lengthy treatment inventions…
So, if you´re worried about Alzheimer´s or keeping your brain sharp into your old age, step up your exercise!
References:
https://ma1.mdedge.com/neurology/article/269489/alzheimers-cognition/irisin-shows-potential-alzheimers-disease-biomarker
https://hsci.harvard.edu/news/hormone-irisin-found-confer-benefits-exercise-cognitive-function
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