Inflammation and iron – what´s the connection?
Iron is a vital nutrient, responsible for maintaining energy levels, cognitive function, immune strength, and muscle health…
But new research suggests that inflammation may severely hinder iron absorption, especially in older adults…
A recent German study has identified a critical threshold for the inflammation marker, C-reactive protein (CRP)…
Increased levels, which correspond with increased inflammation, correlates with reduced iron uptake in the gut, potentially making standard supplementation ineffective for seniors.
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Delving deeper into inflammation´s role in iron deficiency…
Iron deficiency is common among hospitalised older patients, often occurring alongside chronic inflammation.
This study aimed to determine a CRP threshold at which iron absorption becomes significantly impaired, which explains why some patients don´t benefit from iron supplements.
Conducted between October 2023 and February 2024 in a geriatric acute care unit, this retrospective, cross-sectional study analysed 59 hospitalised older patients (mean age: 82.7 years).
Researchers measured participants’ baseline serum iron and CRP levels before breakfast and administered two 100mg iron (II) glycine sulphate capsules.
The absorption was then calculated based on increases in serum iron levels two and four hours post-ingestion, with an increase of 100 μg/dL considered successful absorption.
The results showed that patients with CRP levels below 5mg/dL showed adequate iron absorption after supplementation, but absorption declined sharply as CRP increased…
The most severe drop was seen at levels ≥10.1 mg/dL, where iron absorption was nearly nonexistent.
Iron deficiency can contribute to fatigue, dizziness, weakness, poor immune response, and reduced physical resilience…
These are common symptoms often attributed to ageing rather than nutrient depletion.
If inflammation is actively blocking iron absorption, increasing iron intake alone won’t solve the issue. This research underscores the need to address inflammation first, rather than solely focusing on iron levels.
How to help lower CRP levels naturally…
* Omega-3 fatty acids (found in salmon, walnuts, and flaxseeds) counteract inflammation.
* Leafy greens and berries contain antioxidants that neutralise inflammatory responses.
* Olive oil and turmeric possess powerful anti-inflammatory effects.
* Cutting out processed foods, excessive sugar, and unhealthy fats helps prevent chronic inflammation.
* Even light exercise can lower CRP levels and improve circulation, which supports iron transport. Walking, stretching, and resistance exercises can make a noticeable difference.
* Chronic stress triggers inflammatory processes. Practising meditation, deep breathing, and ensuring adequate sleep can lower CRP levels naturally.
* Curcumin: Proven to significantly decrease CRP levels.
* Quercetin: A potent antioxidant that combats inflammation.
* Magnesium: Plays a crucial role in muscle and nerve function, supporting inflammatory balance.
Remember to check with your doctor before starting on any new supplements, including iron supplements as high dosages can be harmful…
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